Interactions of bosutinib with drug transporters: In vitro and In vivo inhibition of organic cation transporter 2, multidrug and toxin extrusion protein 1, and breast cancer resistance protein by bosutinib, Biomedicine & Pharmacotherapy [LINK]
Min-Ji Kang, Min Ju Kim, Yunjin Seol, Ji-Eun Chang, Kyeong-Ryoon Lee*, Yoon-Jee Chae*
Drug Interaction-Informed Approaches to Inflammatory Bowel Disease Management, Pharmaceutics [LINK]
Kyeong-Ryoon Lee, Aneela Gulnaz, Yoon-jee Chae*
A Phase I, Open-Label, Sequential, Single-Dose Clinical Trial to Evaluate the Pharmacokinetic, Pharmacodynamic, and Safety of IVL3001, a Finasteride-Based Novel Long-Acting Injection for Androgenetic Alopecia, Advances in Therapy [LINK]
Heesun Kim, Choongho Ryu, Kyeong-Ryoon Lee, and Juhee Kim*
Pharmacokinetic interactions of niclosamide in rats: Involvement of organic anion transporters 1 and 3 and organic cation transporter 2, Chemico-Biological Interactions [LINK]
Min-ji Kang, Min Ju Kim, Aeran Kim, Tae-Sung Koo, Kyeong-Ryoon Lee*, Yoon-Jee Chae*
Evaluation of Drug Blood-Brain-Barrier Permeability Using a Microfluidic Chip, Pharmaceutics [LINK]
Jung Yoon Yang, Dae-Seop Shin, Moonkyu Jeong, Seong Soon Kim, Ha Neul Jeong, Byung Hoi Lee, Kyu-Seok Hwang, Yuji Son, Hyeon-Cheol Jeong, Chi-Hoon Choi, Kyeong-Ryoon Lee*, Myung Ae Bae*
Roles of breast cancer resistance protein and organic anion transporting polypeptide 2B1 in gastrointestinal toxicity induced by SN-38 under inflammatory conditions, Toxicology Letters [LINK]
Aneela Gulnaz, Kyeong-Ryoon Lee, Min-Ji Kang, Ji-Eun Chang, Yoon-Jee Chae*
Quality by design-based approach for the development of an analytical method for quantifying ponatinib in rat plasma, Heliyon [LINK]
Nahyun Koo, Eun Ji Lee, Min Ju Kim, Minjung Park, Kyeong-Ryoon Lee, Yoon-Jee Chae*
Proline-Hinged α-Helical Peptides Sensitize Gram-Positive Antibiotics, Expanding Their Physicochemical Properties to Be Used as Gram-Negative Antibiotics, Journal of Medicinal Chemistry [LINK]
Yoonhwa Choi, Hyeong Woon Choe, Minsoo Kook, Seolah Choo, Tae Woo Park, Soeun Bae, Heeseung Kim, Jihye Yang, Woo-Seong Jeong, Jiyoung Yu, Kyeong-Ryoon Lee, Yang Soo Kim, and Jaehoon Yu*
A preliminary study of pharmacokinetics and pharmacodynamics of oral fingolimod in dogs, in vivo [LINK]
Taesik Yun, Jong-Woo Jeong, YoonHoi Koo, Yeon Chae, DoHee Lee, HakHyun Kim, SooChong Kim, Mhan-Pyo Yang, Kyeong-Ryoon Lee, Byeong-Teck Kang*
strong inhibition of organic cation transporter 2 bt flavonoids and attenuation effects on cisplatin-induced cytotoxicity, Chemico-Biological Interactions [LINK]
Kwang-Hee Shin, Kyeong-Ryoon Lee, Min-Ji Kang, Yoon-Jee Chae*
physiologically based pharmacokinetic modeling to predict pharmacokinetics of enavogliflozin, a sodium-dependent glucose transporter 2 inhibitor, in humans, Pharmaceutics [LINK]
Min-Soo Kim, Yoo-Kyung Song, Ji-Soo Choi, Hye Young Ji, Eunsuk Yang, Joon Seok Park, Hyung Sik Kim, Min Joo Kim, In Kyung Cho, Suk-Jae Chung, Yoon-Jee Chae*, and Kyeong-Ryoon Lee*
a mechanism-based undersranding of altered frug pharmacokinetics by gut microbita, Journal of Pharmaceutical Investigation [LINK]
Aneela Gulnaz, Ji-Eun Chang, Han-Joo Maeng, Kwang-Hee Shin, Kyeong-Ryoon Lee*, Yoon-Jee Chae*
Highly specific chimeric DNA-RNA-guided genome editing with enhanced CRISPR-Cas12a system, Molecular Therapy-Nucleic Acids [LINK]
Hanseop Kim, Wi-jae Lee, Chan Hyoung Kim, Yeounsun Oh, Lee Wha Gwon, Hyomin Lee, Woojeung Song, Junho K. Hur, Kyung-Seob Lim, Kang Jin Jeong, Ki-Hoan Nam, Young-Suk Won, Kyeong-Ryoon Lee, Youngjeon Lee, Young-Hyun Kim, Jae-Won Huh, Bong-Hyun Jun*, Dong-Seok Lee*, Seung Hwan Lee*
pharmacokinetics of fluconazole after oral afministration to healthy beagle dogs,Veterinary Dermatology [LINK]
Yujin Choi, Yoonhoi Koo, Taesik Yun, Yeon Chae, Dohee Lee, Jong-Woo Jeong, Kyeong-Ryoon Lee, Hakhyun Kim, Mhan-Pyo Yang, Byeong-Teck Kang*
findings on in vitro transporter-mediated drug interactions and their folow-up actions for labeling : analysis of drug approved by US FDA between 2017 and 2021, Pharmaceutics [LINK]
Kyeong-Ryoon Lee, Ji-Eun Chang, Jongmin Yoon, Hyojeong Jin, and Yoon-Jee Chae*
Sensitive and valid assay for reliable evaluation of drug interactions mediated by human organic anion transporter 1 and 3 using 5-carboxyfluorescein, Analytical Sciences [LINK]
Kyeong-Ryoon Lee; J E Chang; Y J Chae*
bioanalysis of alpelisib using piquid chromatography-tendem mass spectrometry and application to pharmacokinetic study, Journal of Analytical Science and Technology [LINK]
Seop Lee, Min‑Soo Kim, Jong Woo Jeong, Jung‑woo Chae, Tae‑Sung Koo, Han‑Joo Maeng, Suk‑Jae Chung, Kyeong-Ryoon Lee* and Yoon‑Jee Chae*
A population PK-PD model of YH4808, a novel P-CAB, and intragastric pH that incorporated negative feedback by increased intragastric pH onto the systemic exposure to YH4808, CPT: Pharmacometrics & Systems Pharmacology [LINK]
Tae Kyu Chung, Hyun A. Lee, Kyeong-Ryoon Lee, Seong Bok Jang, Kyung- Sang Yu, Howard Lee*
Integration of a physiologically based pharmacokinetic and pharmacodynamic model for tegoprazan and its metabolite: application for predicting food effect and intragastric pH alterations, Pharmaceutics [LINK]
Hyeon-Cheol Jeong, Min-Gul Kim, Zhuodu Wei, Kyeong-Ryoon Lee, Jaehyeok Lee, Im-Sook Song, Kwang-Hee Shin*
In Vivo Toxicity and Pharmacokinetics of Polytetrafluoroethylene Microplastics in ICR Mice, Polymers [LINK]
Sijoon Lee, Kyung-Ku Kang, Soo-Eun Sung, Joo-Hee Choi, Minkyoung Sung, Keum-Yong Seong, Jian Lee, Subin Kang, Seong Yun Yang, Sunjong Lee, Kyeong-Ryoon Lee, Min-Soo Seo*, and KilSoo Kim*
Model-Based Prediction of Acid Suppression and Proposal of a New Dosing Regimen of Fexuprazan in Humans, Pharmaceuticals [LINK]
Min-Soo Kim, Nora Lee, Areum Lee, Yoon-Jee Chae, Suk-Jae Chung*, Kyeong-Ryoon Lee*
Role of the efflux transporters Abcb1 and Abcg2 in the brain distribution of olaparib in mice, European Journal of Pharmaceutical Sciences [LINK]
Yoo-Kyung Song, Min-Ju Kim, Min-Soo Kim, Ji Hun Lee, Suk-Jae Chung, Jin Sook Song, Yoon-Jee Chae*, Kyeong-Ryoon Lee*
Bioanalysis of niclosamide in plasma using liquid chromatography-tandem mass and application to pharmacokinetics in rats and dogs, Journal of Chromatography B [LINK]
Hae-In Choi, Taeheon Kim, Seung-Won Lee, Jin Woo Kim, Yoon Ju Noh, Gwan-Young Kim, Hyun- Jin Park, Yoon-Jee Chae, Kyeong-Ryoon Lee, Soo-Jin Kim*, Tae-Sung Koo*
Regulation of drug transporters by microRNA and implications in disease treatment, Journal of Pharmaceutical Investigation [LINK]
Yoon‑Jee Chae, Ji‑Eun Chang, Mi‑Kyung Lee, Juhee Lim, Kwang‑Hee Shin, Kyeong‑Ryoon Lee*
Interplay among Conformation, Intramolecular Hydrogen Bonds, and Chameleonicity in the Membrane Permeability and Cyclophilin A Binding of Macrocyclic Peptide Cyclosporin O Derivatives, Journal of Medicinal Chemistry [LINK]
Dongjae Lee, Sungjin Lee, Jieun Choi, Yoo-Kyung Song, Min Ju Kim, Dae-Seop Shin, Myung Ae Bae, Yong-Chul Kim, Chin-Ju Park*, Kyeong-Ryoon Lee*, Jun-Ho Choi*, and Jiwon Seo*
Structure-based modification of pyrazolone derivatives to inhibit mTORC1 by targeting the leucyl-tRNA synthetase-RagD interaction, Bioorganic Chemistry [LINK]
Jae Hyun Kim, Kilsoo Jung, Chulho Lee, Doona Song, Kibum Kim, Hee Chan Yoo, Seung Joon Park, Jong Soon Kang, Kyeong-Ryoon Lee, Sunghoon Kim, Jung Min Han, Gyoonhee Han*
Engineering Yarrowia lipolytica for de novo production of tetraacetyl phytosphingosine, Journal of Applied Microbiology [LINK]
Changpyo Han, Minjeong Jang, Min Ju Kim, Man-Ho Han, Kyeong-Ryoon Lee, Ji-Sook Hahn, Jungoh Ahn*
Population pharmacokinetic method to predict within-subject variability using single-period clinical data, Pharmaceuticals [LINK]
Won-ho Kang, Jae-yeon Lee, Jung-woo Chae, Kyeong-Ryoon Lee, In-hwan Baek, Min-Soo Kim, Hyun-moon Back, Sangkeun Jung, Craig Shaffer, Rada Savic*, and Hwi-yeol Yun*
Pharmacokinetic estimation models-based approach to predict clinical implications for CYP induction by calcitriol in human cryopreserved hepatocytes and HepaRG cells, Pharmaceutics [LINK]
Yoon-Jee Chae, Min-Soo Kim, Suk-Jae Chung, Mi-Kyung Lee, Kyeong-Ryoon Lee*, and Han-Joo Maeng*
Pharmacokinetic characterization of supinoxin and its physiologically based pharmacokinetic modeling in rats, Pharmaceutics [LINK]
Yoo-Kyung Song, Yun-Hwan Seol, Min Ju Kim, Jong-Woo Jeong, Hae-In Choi, Seung-Won Lee, Yoon-Jee Chae, Sunjoo Ahn, Young-Dae Gong, Kyeong-Ryoon Lee*, and Tae-Sung Koo*
Development of physiologically based pharmacokinetic model for orally administered fexuprazan in humans, Pharmaceutics [LINK]
Yoo-Seong Jeong, Min-Soo Kim, Nora Lee, Areum Lee, Yoon-Jee Chae, Suk-Jae Chung*,and Kyeong-Ryoon Lee*
The development of a functional human small intestinal epithelium model for drug absorption, Science advances [LINK]
Ohman Kwon(1), Kwang Bo Jung, Kyeong-Ryoon Lee, Ye Seul Son, Hana Lee, Jong-Jin Kim, Kwangho Kim, Seop Lee, Yoo-Kyung Song, Jaeeun Jung, Kunhyang Park, Dae-Soo Kim, Myung Jin Son, Mi-Ok Lee, Tae-Su Han, Hyun-Soo Cho, Soo Jin Oh, Haeun Chung, Sang-Heon Kim, Kyung-Sook Chung, Janghwan Kim*, Cho-Rok Jung*, and Mi-Young Son*
Neurochemical and behavioral analysis by acute exposure to bisphenol A in zebrafish larvae model, Chemosphere [LINK]
Seong Soon Kim, Kyu-Seok Hwang, Jung Yoon Yang, Jin SilChae, Geum Ran Kim, Hyemin Kan, Myeong Hun Jung, Ha-Yeon Lee, Jin Sook Song, Sunjoo Ahn, Dae-Seop Shin, Kyeong-Ryoon Lee, Sang Kyum Kim, Myung Ae Bae*
A machine learning-based identification of genes affecting the pharmacokinetics of tacrolimus using the DMETTM plus platform, International journal of molecular sciences, International journal of molecular sciences [LINK]
Jeong-An Gim, Yonghan Kwon, Hyun A Lee, Kyeong-Ryoon Lee, Soohyun Kim, Yoonjung Choi, Yu Kyong Kim, and Howard Lee*
Development and validation of an LC-MS/MS method for monitoring larotrectinib, a tropomyosin-related kinase inhibitor, in mouse and human plasma and application to pharmacokinetic studies, Journal of Analytical Science and Technology [LINK]
Yoon-Jee Chae, Yoo-Kyung Song, Song-Hee Chae, Min Ju Kim, Jong Soon Kang, Jae-Young Lee, Tae-Sung Koo*, Kyeong-Ryoon Lee*
Development of a polo-like kinase-1 polo-box domain inhibitor as a tumor growth suppressor in mice models, Journal of medicinal chemistry [LINK]
Pethaiah Gunasekaran, Min Su Yim, Mija Ahn, Nak-Kyun Soung, Jung-Eun Park, Jaehi Kim, Geul Bang, Sang Chul Shin, Joonhyeok Choi, Minkyoung Kim, Hak Nam Kim, Young-Ho Lee, Young-Ho Chung, Kyeong Lee, Eunice EunKyeong Kim, Young-Ho Jeon, Min Ju Kim, Kyeong-Ryoon Lee, Bo-Yeon Kim, Kyung S. Lee, Eun Kyoung Ryu*, and Jeong Kyu Bang*
Determination of motolimod concentration in rat plasma by liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study, Journal of Pharmaceutical and Biomedical Analysis [LINK]
Yu-Geun Ji, Yu-Mi Shin, Jong-Woo Jeong, Hae-In Choi, Seung-Won Lee, Jong-Hwa Lee, Kyeong-Ryoon Lee*, Tae-Sung Koo*
Inhibition of skin inflammation by scytonemin, an ultraviolet sunscreen pigment, Marine Drugs [LINK]
Moo Rim Kang, Sun Ah Jo, Hyunju Lee, Yeo Dae Yoon, Joo-Hee Kwon, Jeong-Wook Yang, Byeong Jo Choi, Ki Hwan Park, Myeong Youl Lee, Chang Woo Lee, Kyeong-Ryoon Lee and Jong Soon Kang*
Quercetin is a flavonoid breast cancer resistance protein inhibitor with an impact on the oral pharmacokinetics of sulfasalazine in rats, Pharmaceutics [LINK]
Yoo-Kyung Song, Jin-Ha Yoon, Jong Kyu Woo, Ju-Hee Kang, Kyeong-Ryoon Lee, Seung Hyun Oh, Suk-Jae Chung*, and Han-Joo Maeng*
Determination of Penicillium griseofulvum-oriented pyripyropene A, a selective inhibitor of acyl-coenzyme A: cholesterol acyltransferase 2, in mouse plasma using liquid chromatography-tandem mass spectrometry and its application to pharmacokinetic studies, Biomedical Chromatography [LINK]
Kyeong-Ryoon Lee, Song-Hee Chae, Min Ju Kim, Yoon-Jee Chae, Myung Yeol Lee, Chang Woo Lee, Jong Soon Kang, Won-Kee Yoon, Young-Suk Won, Kihoon Lee, Og-Sung Moon, Young-Kook Kim, Hyoung-Chin Kim*
Extrapolation of in vivo hepatic clearance from in vitro uptake clearance by suspended human hepatocytes for anionic drugs with high binding to human albumin: improvement of in vitro-to-in vivo extrapolation by considering the “albumin-mediated” hepatic uptake mechanism on the basis of the “facilitated-dissociation model”, Drug Metabolism and Disposition [LINK]
Soo-Jin Kim, Kyeong-Ryoon Lee, Seiji Miyauchi, Yuichi Sugiyama*
A physiologically-based pharmacokinetic model adequately predicted the human pharmacokinetic profiles of YH4808, a novel K+-competitive acid blocker, European Journal of Pharmaceutical Sciences [LINK]
Hyun A. Lee, Kyeong-Ryoon Lee, Seong Bok Jang, Soo Yong Chung, Kyung-Sang Yu , Howard Lee*
Functional fragments of AIMP1-derived peptide (AdP) and optimized hydrosol for their topical deposition by Box-behnken design, Molecules [LINK]
Jeong-Jun Lee, Young-Min Han, Tae-Wan Kwon, Dong Hyun Kim, Han Sol Lee, Woo Jin Jung, Jina Kim, Sujin Kang, Sang Kyum Kim, Cheong-Weon Cho, Kyeong-Ryoon Lee, Dae-Duk Kim, Min Chul Park*, Jae-Young Lee*
Model-based pharmacokinetic and pharmacodynamic analysis for acute effects of a small molecule inhibitor of diacylglycerol acyltransferase-1 in the TallyHo/JngJ polygenic mouse, Xenobiotica [LINK]
Yoon-Jee Chae, Jin Sook Song, Jin Hee Ahn, Myung Ae Bae, Kyeong-Ryoon Lee*
The phenomenon of albumin-mediated hepatic uptake of organic anion transport polypeptide substrates: prediction of the in vivo uptake clearance from the in vitro uptake by isolated hepatocytes using a facilitated-dissociation model, Drug Metabolism and Disposition [LINK]
Seiji Miyauchi, Masayuki Masuda, Soo-Jin Kim, Yuudai Tanaka, Kyeong-Ryoon Lee, Shouko Iwakado, Momoko Nemoto, Shotaro Sasaki, Kazumi Shimono, Yoshio Tanaka, Yuichi Sugiyama*
Development of a liquid chromatography-tandem mass spectrometry method for assaying cenobamate in rat plasma, Journal of Liquid Chromatography & Related Technologies [LINK]
Ji-Hoon Oh, Jong-Woo Jeong, Yu-Geun Ji, Yu-Mi Shin, Kyeong-Ryoon Lee, Kwan Hyung Cho, Tae-Sung Koo*
Identification of metabolites of MDR-1339, an inhibitor of beta-amyloidprotein aggregation, and kinetic characterization of the majormetabolites in rats, Journal of Pharmaceutical and Biomedical Analysis [LINK]
Jun-Hyeng Son, Yoo-Seong Jeong, Jong-Hwa Lee, Min-Soo Kim, Kyeong-Ryoon Lee, Chang-Koo Shim, Young Ho Kim, Suk-Jae Chung*
Pharmacokinetics of tafamidis, a transthyretin amyloidosis drug, in rats, Xenobiotica [LINK]
Kyeong-Ryoon Lee, Jong-Woo Jeong, Hun-Chan Hyun, Eunseo Jang, Sunjoo Ahn, Sungwook Choi, Sang Hoon Joo, Sungsub Kim*, Tae-Sung Koo*
Specific inhibition of the distribution of lobeglitazone to the liver by atorvastatin in rats: evidence for a rat organic anion transporting polypeptide 1B2-mediated interaction in hepatic transport, Drug Metabolism and Disposition [LINK]
Chang-Soon Yim, Yoo-Seong Jeong, Song-Yi Lee, Wonji Pyeon, Heon-Min Ryu, Jong-Hwa Lee, Kyeong-Ryoon Lee, Han-Joo Maeng, Suk-Jae Chung*
Feasibility of the functional expression of the human organic anion transporting polypeptide 1B1 (OATP1B1) and its genetic variant 521T/C in the mouse liver, European Journal of Pharmaceutical Sciences [LINK]
Yoon-Jee Chae, Kyeong-Ryoon Lee, Jong-Hwa Lee, Wooin Lee, Dae-Duk Kim, Suk-Jae Chung*, Han-Joo Maeng*
Zebrafish as a screening model for testing the permeability of blood-brain barrier to small molecules, Zebrafish [LINK]
Seong Soon Kim, So Hee Im, Jung Yoon Yang, Yu-Ri Lee, Geum Ran Kim, Jin Sil Chae, Dae-Seop Shin, Jin Sook Song, Sunjoo Ahn, Byung Hoi Lee, Jae Chun Woo, Jin Hee Ahn, Chang Soo Yun, Phiho Kim, Hyoung Rae Kim, Kyeong-Ryoon Lee*, and Myung Ae Bae*
Predicted drug-induced bradycardia related cardio toxicity using a zebrafish in vivo model is highly correlated with results from in vitro tests, Toxicology letters [LINK]
Myoung Joo Park, Kyeong-Ryoon Lee, Dae-Seop Shin, Hang-Suk Chun, Cheol-Hee Kim, Sung-Hoon Ahn, Myung Ae Bae*
Pharmacokinetics of enzalutamide, an anti-prostate cancer drug, in rats, Archives of pharmacal research [LINK]
Tae-Heon Kim, Jong-Woo Jeong, Ji-Hye Song, Kyeong-Ryoon Lee, Sunjoo Ahn, Sung-Hoon Ahn, Sungsub Kim*, Tae-Sung Koo*
In vitro and in vivo anti-inflammatory effects of a novel 4,6-bis ((E)-4-hydroxy-3-methoxystyryl)-1-phenethylpyrimidine-2(1 H)-thione, Chemical research in toxicology [LINK]
Jong Hun Lee, Kyeong-Ryoon Lee, Zheng-Yuan Su, Sarandeep S-S Boyanapalli, Dipti N Barman, Mou-Tuan Huang, Lin Chen, Sadgopan Magesh, Longqin Hu, Ah-Ng Tony Kong*
Nrf2-target approaches in cancer chemoprevention mediated by dietary phytochemicals, Cancer Prevention: Dietary Factors and Pharmacology [LINK]
Francisco Fuentes, Limin Shu, Jong Hun Lee, Zheng-Yuan Su, Kyeong-Ryoon Lee, Ah-Ng Tony Kong*
HS-133, a novel fluorescent phosphatidylinositol 3-kinase inhibitor as a potential imaging and anticancer agent for targeted therapy, Oncotarget [LINK]
Ju-Hee Lee, Kyung Hee Jung, Hyunseung Lee, Mi Kwon Son, Sun-Mi Yun, Sung-Hoon Ahn, Kyeong-Ryoon Lee, Soyoung Lee, Donghee Kim, Sungwoo Hong, Soon-Sun Hong*
Determination of PF-04620110, a novel inhibitor of diacylglycerol acyltransferase-1, in rat plasma using liquid chromatography-tandem mass spectrometry and its application in pharmacokinetic studies, Biomedical Chromatography [LINK]
Kyeong-Ryoon Lee, Sung Heum Choi, Jin-Sook Song, Hyewon Seo, Yoon-Jee Chae, Hwang Eui Cho, Jin Hee Ahn, Sung-Hoon Ahn, Myung Ae Bae*
Determination of 2-aryl-7(3',4'-dialkoxyphenyl)-pyrazolo [1,5-alpha] pyrimidine, a novel phosphodiesterase-4 inhibitor, in rat plasma by liquid chromatography-tandem mass spectrometry, Journal of chromatographic science [LINK]
Kyeong-Ryoon Lee, Jin Sook Song, Yoon-Jee Chae, Min-Sun Kim, Sung-Heum Choi, Dong Ju Jeon, Myung Ae Bae, Sung-Hoon Ahn*
Pharmacokinetic characterization of the novel TAZ modulator TM-25659 using a multicompartment kinetic model in rats and a possibility of its drug-drug interactions in humans, Xenobiotica [LINK]
Kyeong-Ryoon Lee, Sung Heum Choi, Jin-Sook Song Eun-Young Kwak, Yoon-Jee Chae, So Hee Im, Byung Hoi Lee, Hyewon Seo, Woon-Ki Cho, Min-Sun Kim, Nak Jeong Kim, Sung-Hoon Ahn, Myung Ae Bae*
A sensitive and selective LC-MS method for the determination of lurasidone in rat plasma, bile, and urine, Chromatographia [LINK]
Yoon-Jee Chae, Tae-Sung Koo, Kyeong-Ryoon Lee*
Pharmacokinetics and pharmacodynamics of KR-66223, a novel DPP-4 inhibitor, Drug Metabolism and Pharmacokinetics [LINK]
Jin Sook Song, Kyeong-Ryoon Lee, Hyun Jin Kwon, Sang Dal Rhee, Min Sun Kim, Sung Hum Choi, Sung-Hack Lee, Im Sook Song, Jin Hee Ahn, Sung Hoon Ahn, Myung Ae Bae*
Quantification of cilnidipine in human plasma by liquid chromatography-mass spectrometry, Journal of liquid chromatography & related technologies [LINK]
Kyeong-Ryoon Lee, Yoon-Jee Chae, Jong-Hwa Lee, Dae-Duk Kim, Saeho Chong, Chang-Koo Shim, Suk-Jae Chung*
Determination of a novel TAZ modulator, 2-butyl-5-methyl-6-(pyridine-3-yl)-3-[2-(1H-tetrazole-5-yl)-biphenyl-4-ylmethyl]-3H imidazo[4,5-b]pyridine] (TM-25659) in rat plasma by liquid chromatography-tandem mass spectrometry, Journal of pharmaceutical and biomedical analysis [LINK]
Sung Heum Choi, Kyeong-Ryoon Lee, Jae-Chun Woo, Nak Jeong Kim, Dong Cheul Moon, Eun Sook Hwang, Sung-Hoon Ahn, Myung Ae Bae, Min-Sun Kim*
Development of a LC-MS method for quantification of FK-3000 and its application to in vivo pharmacokinetic study in drug development, Journal of pharmaceutical and biomedical analysis [LINK]
Jong-Hwa Lee, Yoon-Jee Chae, Kyeong-Ryoon Lee, Sung-Hoon Ahn, Joung-Wook Seo, Qing-Ri Jin, Young-Ah Woo, Gye-Won Lee, Soon-Chang Cho, Sung-Won Kwon*, Dae-Hun Park*
Functional consequences of genetic variations in the human organic anion transporting polypeptide 1B3 (OATP1B3) in the Korean population, Journal of pharmaceutical sciences [LINK]
Yoon-Jee Chae, Kyeong-Ryoon Lee, Chi-Kyung Noh, Saeho Chong, Dae-Duk Kim, Chang-Koo Shim, Suk-Jae Chung*
A strategy for reducing particulate contamination on opening glass ampoules and development of evaluation methods for its application, Drug Development and Industrial Pharmacy [LINK]
Kyeong-Ryoon Lee, Yoon-Jee Chae, Sung-Eel Cho, Suk-Jae Chung*
Determination of zabofloxacin in rat plasma by liquid chromatography with mass spectrometry and its application to pharmacokinetic study, Journal of pharmaceutical and biomedical analysis [LINK]
Hyo-Eon Jin, Kyeong-Ryoon Lee, In-Hyul Kang, Suk-Jae Chung, Chang-Koo Shim*
Quantification of oltipraz using liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study in rat plasma, ournal of pharmaceutical and biomedical analysis [LINK]
Jong-Hwa Lee, Hwanmi Lim, Do-Geun Kim, Dae-Hun Park, Young-Ah Woo, Hyun-Jung Noh, Qing-Ri Jin, Kyeong-Ryoon Lee, Gye-Won Lee, Choong-Yong Kim*
Physiologically based pharmacokinetic modeling of SNU-0039, an anti-Alzheimer's agent, in rats, Journal of pharmacokinetics and pharmacodynamics [LINK]
Kyeong-Ryoon Lee, Yoon-Jee Chae, Han-Joo Maeng, Jeewoo Lee, Dae-Duk Kim, Saeho Chong, Chang-Koo Shim, Suk-Jae Chung*
Pharmacokinetic characterization of decursinol derived from Angelica gigas Nakai in rats, Xenobiotica [LINK]
Jin Sook Son g, Jung-Woo Chae, Kyeong-Ryoon Lee, Byung Hoi Lee, Eun Jeong Choi, Sung Hoon Ahn, Kwang-il Kwon, Myung Ae Bae*
Pharmacokinetics of lurasidone, a novel atypical anti-psychotic drug, in rats, Xenobiotica [LINK]
Kyeong-Ryoon Lee, Yoon-Jee Chae, Tae-Sung Koo*
Simultaneous determination of artesunate and dihydroartemisinin concentrations in human plasma by high performance liquid chromatography-mass spectrometry with electro-spray ionization, Analytical letters [LINK]
Kyeong-Ryoon Lee , Han-Joo Maeng, Mi-Hwa Kim, Dae-Duk Kim, Chang-Koo Shim , Suk-Jae Chung*
Lack of a primary physicochemical determinant in the direct transport of drugs to the brain after nasal administration in rats: potential involvement of transporters in the pathway, Drug metabolism and pharmacokinetics [LINK]
Kyeong-Ryoon Lee, Han-Joo Maeng, Jung-Byung Chae, Saeho Chong, Dae-Duk Kim, Chang-Koo Shim, Suk-Jae Chung*
Evidence of carrier-mediated transport in the penetration of donepezil into the rat brain, Journal of pharmaceutical sciences [LINK]
Mi‐Hwa Kim‡ , Han‐Joo Maeng‡, Kyung‐Ha Yu‡, Kyeong‐Ryoon Lee‡, Takashi Tsuruo, Dae‐Duk Kim, Chang‐Koo Shim, Suk‐Jae Chung*